Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | NPEPPS | P55786 | 8/20 | 0.42 |
| ▸ | ANPEP | P15144 | 7/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17032321 | 0.91 | LMNA (0.62) | LMNAADORA2AADORA2BNPEPPSANPEP | |
| SCHEMBL26808463 | 0.89 | LMNA (0.55) | LMNAADORA2AADORA2BNPEPPSANPEP | |
| SCHEMBL29313524 | 0.88 | LMNA (0.58) | LMNAADORA2AADORA2BNPEPPSANPEP | |
| SCHEMBL16203604 | 0.84 | LMNA (0.62) | LMNAADORA2AADORA2BNPEPPSANPEP | |
| SCHEMBL18512597 | 0.84 | LMNA (0.62) | LMNAADORA2AADORA2BNPEPPSANPEP | |
| SCHEMBL20149800 | 0.84 | LMNA (0.61) | LMNAADORA2AADORA2BNPEPPSANPEP | |
| SCHEMBL31160186 | 0.84 | LMNA (0.66) | LMNAADORA2AADORA2BNPEPPSANPEP | |
| SCHEMBL25765149 | 0.82 | PRMT6 (0.53) | — | |
| SCHEMBL26553794 | 0.82 | PRMT6 (0.53) | — | |
| SCHEMBL13084455 | 0.82 | LMNA (0.70) | LMNAADORA2AADORA2BP2RX3P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365970-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | NSUN2, SNRPA, SNRPF | LMNA 737/4885ADORA2A 509/4885ADORA2B 837/4885 |
| US-20230332153-A1 | Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof | NSUN2, SNRPA, SNRPF | LMNA 737/4885ADORA2A 509/4885ADORA2B 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.