Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437064 | 1.00 | MTNR1A (0.48) | MTNR1AMTNR1BBCHEELANE | |
| SCHEMBL26554383 | 0.95 | MTNR1A (0.50) | MTNR1AMTNR1BELANE | |
| SCHEMBL29437088 | 0.95 | MTNR1A (0.50) | MTNR1AMTNR1BELANE | |
| SCHEMBL25402731 | 0.86 | MTNR1A (0.53) | MTNR1AMTNR1BELANE | |
| SCHEMBL26554385 | 0.85 | TSHR (0.42) | BCHEELANE | |
| SCHEMBL29437053 | 0.85 | TSHR (0.42) | BCHEELANE | |
| SCHEMBL25400647 | 0.81 | MTNR1A (0.55) | MTNR1AMTNR1BELANE | |
| SCHEMBL29437005 | 0.81 | BCHE (0.51) | BCHE | |
| SCHEMBL26554316 | 0.81 | BCHE (0.51) | BCHE | |
| SCHEMBL29437063 | 0.80 | TSHR (0.43) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | SPNS2, SPCS2, SMN1; SMN2 | MTNR1A 847/4885MTNR1B 531/4885BCHE 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.