Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ADK | P55263 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15843910 | 0.84 | TYMS (0.50) | TYMSMEN1KMT2APOLBNPC1 | |
| SCHEMBL31087627 | 0.83 | TYMS (0.43) | TYMSL3MBTL1ATMMEN1KMT2A | |
| SCHEMBL25417476 | 0.80 | HEXA (0.46) | L3MBTL1ATMMEN1KMT2APOLB | |
| SCHEMBL30436709 | 0.80 | HEXA (0.46) | L3MBTL1ATMMEN1KMT2APOLB | |
| SCHEMBL25421298 | 0.78 | TERT (0.49) | L3MBTL1ATMMEN1KMT2APOLB | |
| SCHEMBL17172502 | 0.78 | TYMS (0.53) | TYMSATMMEN1KMT2APOLB | |
| SCHEMBL19449069 | 0.77 | ATM (0.44) | L3MBTL1ATMADK | |
| SCHEMBL11947508 | 0.77 | TYMS (0.37) | TYMSMEN1KMT2APOLB | |
| SCHEMBL25420920 | 0.75 | APP (0.47) | L3MBTL1MEN1KMT2APOLBNPC1 | |
| SCHEMBL14918648 | 0.72 | TYMS (0.47) | TYMSATMMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331679-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | PSEN1, PSEN2, MAPT | TYMS 2656/4885TNNI3 1372/4885TNNT2 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.