Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 4/20 | 0.46 |
| ▸ | HEXB | P07686 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25417476 | 1.00 | HEXA (0.46) | HEXAHEXBMEN1KMT2APOLB | |
| SCHEMBL25421298 | 0.87 | TERT (0.49) | HEXAHEXBMEN1KMT2APOLB | |
| SCHEMBL25420920 | 0.84 | APP (0.47) | HEXAHEXBMEN1KMT2APOLB | |
| SCHEMBL26555003 | 0.80 | TYMS (0.44) | MEN1KMT2APOLBNPC1USP2 | |
| SCHEMBL29449407 | 0.79 | MEN1 (0.50) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL26555732 | 0.78 | APP (0.43) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL26556567 | 0.77 | MEN1 (0.53) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL31094030 | 0.76 | MEN1 (0.69) | HEXAHEXBMEN1KMT2APOLB | |
| SCHEMBL26053794 | 0.76 | MEN1 (0.69) | HEXAHEXBMEN1KMT2APOLB | |
| SCHEMBL25420764 | 0.74 | TERT (0.55) | MEN1KMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185567-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2023-05-31 | — | — | EP | claimed |
| EP-4185567-A1 | NAPHTHALENE MONOIMIDE COMPOUNDS AND METHODS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2023-05-31 | — | — | EP | disclosed |