Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LYPLA1 | O75608 | 2/20 | 0.41 |
| ▸ | LYPLA2 | O95372 | 2/20 | 0.41 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26558014 | 0.85 | GLA (0.39) | SMN1; SMN2HTTMAPTHPGDNPC1 | |
| SCHEMBL26558027 | 0.81 | PTAFR (0.37) | ALDH1A1GAAMEN1KMT2ARAB9A | |
| SCHEMBL26558053 | 0.75 | GLA (0.39) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL26558058 | 0.75 | TLR9 (0.35) | NPSR1 | |
| SCHEMBL26558034 | 0.74 | GLA (0.37) | ALDH1A1SMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL26558037 | 0.73 | GLA (0.35) | ALDH1A1SMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL26558059 | 0.72 | CA1 (0.34) | ALDH1A1SMN1; SMN2HTTMEN1HPGD | |
| SCHEMBL26558064 | 0.72 | GLA (0.34) | ALDH1A1SMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL23992569 | 0.70 | TOP2A (0.35) | ALDH1A1SMN1; SMN2HTTMAPTHPGD | |
| SCHEMBL26558038 | 0.70 | GLA (0.34) | ALDH1A1SMN1; SMN2HTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | ALDH1A1 946/4885LYPLA1 2813/4885LYPLA2 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.