Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22811004 | 1.00 | TSHR (0.40) | TSHRLMNAALDH1A1THRBKMT2A | |
| SCHEMBL5839487 | 0.87 | TSHR (0.52) | TSHRLMNAALDH1A1THRBKMT2A | |
| SCHEMBL22994888 | 0.82 | THRB (0.34) | LMNAALDH1A1THRB | |
| SCHEMBL14969719 | 0.80 | TSHR (0.50) | TSHRLMNAALDH1A1THRBKMT2A | |
| SCHEMBL20429066 | 0.80 | TSHR (0.44) | TSHRLMNAALDH1A1THRBKMT2A | |
| SCHEMBL22994948 | 0.80 | LMNA (0.35) | LMNATHRB | |
| SCHEMBL16326363 | 0.79 | HIF1A (0.33) | ALDH1A1THRB | |
| SCHEMBL469080 | 0.78 | TSHR (0.31) | TSHR | |
| SCHEMBL15697261 | 0.77 | TSHR (0.43) | TSHRLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL15697254 | 0.77 | TSHR (0.43) | TSHRLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4261269-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2023-10-18 | — | — | EP | disclosed |