Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 11/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21664248 | 0.87 | PRKDC (0.47) | PRKDCHTR1AHTR7HRH4PDE10A | |
| SCHEMBL26559116 | 0.87 | PRKDC (0.48) | PRKDCHTR1AHTR7HRH4PDE10A | |
| SCHEMBL26558994 | 0.87 | PRKDC (0.48) | PRKDCCYP1A2CYP2D6 | |
| SCHEMBL30562879 | 0.80 | ENPP1 (0.47) | PRKDCHTR1AHTR7HRH4PDE10A | |
| SCHEMBL21664272 | 0.80 | ENPP1 (0.47) | PRKDCHTR1AHTR7HRH4PDE10A | |
| SCHEMBL26559069 | 0.79 | HRH4 (0.44) | PRKDCHTR1AHTR7HRH4PDE10A | |
| Hydrochloric Acid SCHEMBL30562890 | 0.79 | ENPP1 (0.46) | PRKDCHTR1AHTR7HRH4PDE10A | |
| SCHEMBL26553311 | 0.77 | PRKDC (0.44) | PRKDCHTR1AHTR7HRH4PDE10A | |
| SCHEMBL26555631 | 0.77 | BTK (0.44) | PRKDCHTR1AHTR7HRH4BTK | |
| SCHEMBL26181319 | 0.77 | BTK (0.46) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |