Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCRL2 | O00421 | 4/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21664272 | 1.00 | ENPP1 (0.47) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| Hydrochloric Acid SCHEMBL30562890 | 0.99 | ENPP1 (0.46) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL21664248 | 0.93 | PRKDC (0.47) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL21664237 | 0.90 | RAB9A (0.45) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL30562886 | 0.90 | RAB9A (0.45) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL21664364 | 0.88 | ENPP1 (0.44) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL30562988 | 0.88 | RAB9A (0.44) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL21664353 | 0.88 | RAB9A (0.44) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL25554795 | 0.88 | ALDH1A1 (0.44) | ENPP1PTGS1PTGS2RAB9AHRH4 | |
| SCHEMBL21664258 | 0.87 | HTT (0.50) | ENPP1CNR1CNR2PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |