Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 15/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26559079 | 0.87 | PRKDC (0.49) | PRKDCCYP1A2CYP2D6 | |
| SCHEMBL21664254 | 0.87 | ENPP1 (0.48) | PRKDCHTTENPP1 | |
| SCHEMBL26563939 | 0.86 | PRKDC (0.48) | PRKDCHTTPDE3ATP53CYP1A2 | |
| SCHEMBL30562899 | 0.78 | HTT (0.50) | PRKDCHTTCYP1A2ENPP1 | |
| SCHEMBL21664258 | 0.78 | HTT (0.50) | PRKDCHTTCYP1A2ENPP1 | |
| SCHEMBL26552236 | 0.78 | PRKDC (0.47) | PRKDCHTTPDE3ATP53ENPP1 | |
| SCHEMBL26552621 | 0.78 | HTT (0.49) | PRKDCHTTPDE3ATP53ENPP1 | |
| SCHEMBL26563914 | 0.78 | HTT (0.55) | PRKDCHTTPDE3ATP53ENPP1 | |
| SCHEMBL26558976 | 0.76 | HTT (0.50) | PRKDCHTTPDE3ATP53ENPP1 | |
| SCHEMBL21664236 | 0.76 | ENPP1 (0.47) | PRKDCPDE3ATP53ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |