Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662332 | 0.84 | GCK (0.44) | GCK | |
| SCHEMBL2659188 | 0.83 | GCK (0.42) | GCK | |
| SCHEMBL2662402 | 0.83 | GCK (0.43) | GCK | |
| SCHEMBL1042657 | 0.82 | GCK (0.64) | GCKKCNH2 | |
| SCHEMBL2658141 | 0.80 | GCK (0.43) | GCKKCNH2 | |
| SCHEMBL2659314 | 0.76 | GCK (0.55) | GCKKCNH2 | |
| SCHEMBL2662076 | 0.76 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL2659316 | 0.76 | GCK (0.56) | GCK | |
| SCHEMBL2074639 | 0.76 | GCK (0.56) | GCK | |
| SCHEMBL2657812 | 0.75 | GCK (0.54) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078000-A1 | BENZOYL AMINO HETEROCYCLYL COMPOUNDS AS GLUCOKINASE (GLK) ACTIVATORS | AstraZeneca AB (SE) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008050117-A1 | BENZOYL AMINO HETEROCYCLYL COMPOUNDS AS GLUCOKINASE (GLK) ACTIVATORS | ASTRAZENECA AB (SE) | 2008-05-02 | — | — | WO | disclosed |