Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657812 | 0.86 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL2655335 | 0.84 | GCK (0.44) | GCKKCNH2 | |
| SCHEMBL2662076 | 0.81 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL2662747 | 0.81 | GCK (0.43) | GCKKCNH2 | |
| SCHEMBL2656050 | 0.80 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL1427361 | 0.80 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL1042208 | 0.78 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL2662313 | 0.78 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL2657276 | 0.78 | GCK (0.43) | GCKKCNH2 | |
| SCHEMBL2657866 | 0.77 | SMN1; SMN2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078000-A1 | BENZOYL AMINO HETEROCYCLYL COMPOUNDS AS GLUCOKINASE (GLK) ACTIVATORS | AstraZeneca AB (SE) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008050117-A1 | BENZOYL AMINO HETEROCYCLYL COMPOUNDS AS GLUCOKINASE (GLK) ACTIVATORS | ASTRAZENECA AB (SE) | 2008-05-02 | — | — | WO | disclosed |