Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 11/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21664268 | 0.89 | ENPP1 (0.71) | ENPP1PDE3APDE10APDE3BHTR1A | |
| SCHEMBL21664410 | 0.85 | ENPP1 (0.59) | ENPP1PDE3APDE10APDE3BHTR1A | |
| SCHEMBL21664290 | 0.81 | ENPP1 (0.52) | ENPP1PDE3A | |
| SCHEMBL25552086 | 0.80 | ENPP1 (0.53) | ENPP1PDE3A | |
| SCHEMBL21664253 | 0.80 | ENPP1 (0.58) | ENPP1PDE3APDE10APDE3BPIK3CD | |
| SCHEMBL30562935 | 0.80 | ENPP1 (0.58) | ENPP1PDE3APDE10APDE3BPIK3CD | |
| SCHEMBL21664332 | 0.80 | ENPP1 (0.52) | ENPP1PDE3APDE10AHTR1A | |
| SCHEMBL21664291 | 0.79 | ENPP1 (0.50) | ENPP1PDE3A | |
| SCHEMBL30562895 | 0.79 | ENPP1 (0.50) | ENPP1PDE3A | |
| SCHEMBL25551815 | 0.79 | ENPP1 (0.50) | ENPP1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |