Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HNF4A | P41235 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.48 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371177 | 0.88 | TRPV1 (0.60) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL4187499 | 0.87 | TRPV1 (0.59) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL3627156 | 0.85 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL10601679 | 0.84 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL6560636 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL6554125 | 0.82 | LMNA (0.65) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.82 | LMNA (0.73) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL10792509 | 0.81 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2HTTL3MBTL1MAPT | |
| SCHEMBL26564771 | 0.81 | TRPV1 (0.49) | LMNASMN1; SMN2TRPV1 | |
| SCHEMBL2851561 | 0.80 | LMNA (0.61) | LMNASMN1; SMN2HTTL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331663-A1 | SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS | THE CLEVELAND CLINIC FOUNDATION | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331663-A1 | SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS | NQO1, NADK, CD38 | LMNA 1685/4885SMN1; SMN2 2057/4885HNF4A 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.