Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Phenethylcarbamate SCHEMBL6392045 | 0.95 | LMNA (0.67) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL6554125 | 0.94 | LMNA (0.65) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL13884390 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL10305302 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| Benzyl Phenethylcarbamate SCHEMBL27338403 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL8802503 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL9487307 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL160715 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL5511344 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL2851561 | 0.91 | LMNA (0.61) | LMNASMN1; SMN2HTTTGM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754041-A4 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMA (US) | 1997-11-19 | — | — | EP | claimed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | claimed |
| WO-1995026723-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | claimed |
| CN-117800905-A | Preparation method of 4- (2, 6-dimethyl-3-nitropyridin-4-ylamino) phenethyl carbamic acid benzyl ester | 洛阳惠中兽药有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-111164084-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-11173480-B2 | Catalyst in which metal is carried on inorganic porous body having hierarchical porous structure, and method for manufacturing said catalyst | SNG INC. (JP) | 2021-11-16 | — | — | US | disclosed |
| US-20200246779-A1 | CATALYST IN WHICH METAL IS CARRIED ON INORGANIC POROUS BODY HAVING HIERARCHICAL POROUS STRUCTURE, AND METHOD FOR MANUFACTURING SAID CATALYST | SNG INC. (JP) | 2020-08-06 | — | — | US | disclosed |
| CN-111051309-A | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2020-04-21 | — | — | CN | disclosed |
| US-20100292269-A1 | BIR DOMAIN BINDING COMPOUNDS | AEGERA THERAPEUTICS, INC. (CA) | 2010-11-18 | — | — | US | disclosed |
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-06-04 | — | — | US | disclosed |
| US-20070167329-A1 | Plant growth regulation | BAYER CROPSCIENCE GMBH (DE) | 2007-07-19 | — | — | US | disclosed |
| EP-1038874-A1 | OXIME DERIVATIVES AND AGRICULTURAL CHEMICALS CONTAINING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-27 | — | — | EP | disclosed |
| US-5807875-A | OBESITY THERAPY | DR. KARL THOMAE GMBH (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0754041-A4 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMA (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5580878-A | TREATING SLEEP DISORDERS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0680488-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1995-11-08 | — | — | EP | disclosed |
| WO-1995026723-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | disclosed |
| US-5403851-A | Central nervous system and psychological disorders | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1994017090-A1 | 2,6-DIAMINOPURINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11173480-B2 | Catalyst in which metal is carried on inorganic porous body having hierarchical porous structure, and method for manufacturing said catalyst | TMEM63A, PORCN, PIEZO1 | LMNA 4570/4885SMN1; SMN2 4029/4885HTT 3021/4885 |
| US-20070167329-A1 | Plant growth regulation | TOE1, GHITM, GMDS | LMNA 4839/4885SMN1; SMN2 4884/4885HTT 4857/4885 |
| US-20100292269-A1 | BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC3, BIRC2 | LMNA 605/4885SMN1; SMN2 3550/4885HTT 3072/4885 |
| US-20090143279-A1 | Methods and compositions for treating metabolic disorders | PC, PCK2, CS | LMNA 1929/4885SMN1; SMN2 281/4885HTT 345/4885 |
| US-20200246779-A1 | CATALYST IN WHICH METAL IS CARRIED ON INORGANIC POROUS BODY HAVING HIERARCHICAL POROUS STRUCTURE, AND METHOD FOR MANUFACTURING SAID CATALYST | TMEM63A, PORCN, PIEZO1 | LMNA 4570/4885SMN1; SMN2 4029/4885HTT 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.