Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | GABRE | P78334 | 1/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.51 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 8/20 | 0.49 |
| ▸ | KDM5C | P41229 | 6/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14993600 | 0.85 | MBOAT4 (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Lithium Ion SCHEMBL29700415 | 0.84 | KDM5C (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29700435 | 0.83 | KDM4E (0.51) | KDM5BKDM5CKDM4CKDM6BKDM5A | |
| SCHEMBL346941 | 0.83 | KDM4E (0.51) | KDM5BKDM5CKDM4CKDM6BKDM5A | |
| SCHEMBL26567184 | 0.81 | KDM4C (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL17442671 | 0.80 | KDM4D (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1647272 | 0.79 | CYP1A2 (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22637811 | 0.78 | CYP1A2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22637814 | 0.78 | CYP1A2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29478781 | 0.78 | CYP1A2 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043741-A1 | AUTOTAXIN INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 레고켐 바이오사이언스 | 2024-02-29 | — | — | WO | disclosed |
| WO-2024043741-A1 | AUTOTAXIN INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 레고켐 바이오사이언스 | 2024-02-29 | — | — | WO | disclosed |
| US-20230331715-A1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331715-A1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, NR1I3, NR1H4 | GABRP 3750/4885GABRD 2535/4885GABRA1 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.