Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101520 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2PKMNPC1RAB9ACYP1A2 | |
| SCHEMBL26100222 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2PKMNPC1RAB9ACYP1A2 | |
| SCHEMBL26102205 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2PKMNPC1RAB9ACYP1A2 | |
| SCHEMBL23747779 | 0.88 | HPGD (0.67) | SMN1; SMN2NPC1RAB9AHPGDPOLB | |
| SCHEMBL26567135 | 0.88 | HPGD (0.67) | SMN1; SMN2NPC1RAB9AHPGDPOLB | |
| SCHEMBL23747793 | 0.87 | PKM (0.58) | SMN1; SMN2PKMNPC1RAB9ACYP2C9 | |
| SCHEMBL26101993 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2PKMNPC1RAB9AHDAC1 | |
| SCHEMBL23747791 | 0.86 | PKM (0.55) | SMN1; SMN2PKMNPC1RAB9AHDAC1 | |
| SCHEMBL23747575 | 0.86 | DPP4 (0.58) | SMN1; SMN2PKMNPC1RAB9AHDAC1 | |
| SCHEMBL26102253 | 0.86 | DPP4 (0.58) | SMN1; SMN2PKMNPC1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133132-A1 | NAMPT MODULATORS | NAMPT, MC4R, SIRT1 | SMN1; SMN2 1161/4885PKM 401/4885NPC1 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.