Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 17/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26569398 | 0.96 | KDM4E (0.57) | KDM4EALDH1A1TDP1LMNAMAPT | |
| SCHEMBL26111482 | 0.85 | ALDH1A1 (0.74) | KDM4EALDH1A1TDP1LMNAMAPT | |
| SCHEMBL26116157 | 0.82 | KDM4E (0.75) | KDM4EALDH1A1TDP1LMNAMAPT | |
| SCHEMBL30593621 | 0.78 | KDM4E (0.77) | KDM4EALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL26112800 | 0.78 | KDM4E (0.77) | KDM4EALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL26110509 | 0.77 | ALDH1A1 (0.66) | KDM4EALDH1A1TDP1LMNAMAPT | |
| SCHEMBL4071636 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1TDP1LMNAMAPT | |
| SCHEMBL26568013 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1TDP1LMNAKMT2A | |
| SCHEMBL26568771 | 0.73 | ALDH1A1 (0.79) | KDM4EALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL26113339 | 0.72 | KDM4E (0.56) | KDM4EALDH1A1TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023182899-A1 | INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY | Politechnika Gdańska (PL) | 2023-09-28 | — | — | WO | disclosed |