Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 18/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EIF4E | P06730 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110509 | 0.86 | ALDH1A1 (0.66) | KDM4EALDH1A1PKMTDP1LMNA | |
| SCHEMBL26569399 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1PKMLMNAGAA | |
| SCHEMBL26111482 | 0.83 | ALDH1A1 (0.74) | KDM4EALDH1A1PKMTDP1LMNA | |
| SCHEMBL26568831 | 0.82 | KDM4E (0.54) | KDM4EALDH1A1PKMTDP1LMNA | |
| SCHEMBL26113339 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1PKMTDP1LMNA | |
| SCHEMBL26568017 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1PKMLMNAGAA | |
| SCHEMBL4080549 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1PKMTDP1LMNA | |
| SCHEMBL26569398 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1PKMTDP1LMNA | |
| SCHEMBL26569385 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1PKMTDP1LMNA | |
| SCHEMBL4071636 | 0.73 | KDM4E (0.71) | KDM4EALDH1A1PKMTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023182897-A1 | INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY | Politechnika Gdańska (PL) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023182899-A1 | INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY | Politechnika Gdańska (PL) | 2023-09-28 | — | — | WO | disclosed |