Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26113339 | 0.92 | KDM4E (0.56) | KDM4EALDH1A1PKMMAPTNPSR1 | |
| SCHEMBL30593623 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1PKMMAPTNPSR1 | |
| SCHEMBL26112639 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1PKMMAPTNPSR1 | |
| SCHEMBL26568020 | 0.83 | KDM4E (0.65) | KDM4EALDH1A1PKMMAPTNPSR1 | |
| SCHEMBL26111482 | 0.76 | ALDH1A1 (0.74) | KDM4EALDH1A1PKMMAPTNPSR1 | |
| SCHEMBL26110509 | 0.76 | ALDH1A1 (0.66) | KDM4EALDH1A1PKMMAPTNPSR1 | |
| SCHEMBL26568013 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1PKMNPSR1MEN1 | |
| SCHEMBL26568831 | 0.73 | KDM4E (0.54) | KDM4EALDH1A1PKMMAPTNPSR1 | |
| SCHEMBL26113450 | 0.69 | IDH1 (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL30593620 | 0.67 | ALDH1A1 (0.71) | KDM4EALDH1A1PKMMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023182897-A1 | INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY | Politechnika Gdańska (PL) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023182899-A1 | INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY | Politechnika Gdańska (PL) | 2023-09-28 | — | — | WO | disclosed |