Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907760 | 0.82 | KDM4E (0.67) | OGG1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL16898615 | 0.82 | OGG1 (0.63) | OGG1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL25316335 | 0.81 | OGG1 (0.57) | OGG1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL4928682 | 0.81 | MMP1 (0.61) | OGG1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL14290328 | 0.80 | GAA (0.69) | SMN1; SMN2ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL14045867 | 0.77 | OGG1 (0.56) | OGG1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL11358225 | 0.76 | OGG1 (0.61) | OGG1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL4764424 | 0.76 | OGG1 (0.61) | OGG1SMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL16904013 | 0.76 | OGG1 (0.55) | OGG1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL6202193 | 0.75 | KMT2A (0.55) | OGG1ALDH1A1KMT2AMEN1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |