SCHEMBL26568972

SCHEMBL26568972

CCCCOC[C@H]1[C@@H](O)[C@H](n2c[n+](C)c3c(=O)[nH]c(N)nc32)O[C@@H]1C

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HINT1 P49773 5/20 0.38
GSK3A P49840 2/20 0.34
RPS6KA3 P51812 2/20 0.34
MAPK14 Q16539 2/20 0.34
NT5E P21589 1/20 0.34
FUT5 Q11128 1/20 0.34
NOS1 P29475 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34
LMNA P02545 1/20 0.34
EIF4E P06730 1/20 0.33
TLR7 Q9NYK1 2/20 0.33
AHCY P23526 1/20 0.33
TGM2 P21980 1/20 0.33
KRAS P01116 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26568912 0.95 HINT1 (0.39) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26568971 0.95 HINT1 (0.39) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26569371 0.92 HINT1 (0.36) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26568603 0.91 HINT1 (0.40) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26213741 0.90 HINT1 (0.37) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26201457 0.89 HINT1 (0.37) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26202070 0.87 HINT1 (0.39) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26566855 0.87 HINT1 (0.39) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26571022 0.87 HINT1 (0.39) HINT1GSK3ARPS6KA3MAPK14NT5E
SCHEMBL26569369 0.87 HINT1 (0.37) HINT1GSK3ARPS6KA3MAPK14NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261217-A1 COMPOUND FOR RNA CAPPING AND APPLICATION OF COMPOUND Guangzhou Henovcom Bioscience Co., Ltd. (CN) 2023-10-18 EP disclosed