SCHEMBL26569683

SCHEMBL26569683

Cc1cc(C)c(-c2cc(C(C)(C)C)c(C)nc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CA2 P00918 1/20 0.38
POLB P06746 1/20 0.38
TYR P14679 1/20 0.38
PSMB5 P28074 1/20 0.33
HSPA5 P11021 1/20 0.32
CYP2C9 P11712 3/20 0.31
CYP2C19 P33261 3/20 0.31
HIF1A Q16665 2/20 0.31
CYP2D6 P10635 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDGFRB P09619 1/20 0.31
FGFR1 P11362 1/20 0.31
SRC P12931 1/20 0.31
PDGFRA P16234 1/20 0.31
CYP1A2 P05177 1/20 0.31
CRHR1 P34998 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14867639 0.72 CYP2C19 (0.38) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL26569652 0.69 HSP90AA1 (0.33)
SCHEMBL26569655 0.69 PSMB5 (0.50) SMN1; SMN2ALDH1A1PSMB5CYP2C9CYP2C19
SCHEMBL26569654 0.68 KIF11 (0.42) SMN1; SMN2ALDH1A1POLBHSD17B10
SCHEMBL26569685 0.68 CYP2C9 (0.33) CYP2C9CYP2C19CRHR1
SCHEMBL21265843 0.68 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL26569653 0.66 PSMB5 (0.33) ALDH1A1PSMB5CYP2C9CYP2C19CYP1A2
SCHEMBL23872363 0.64 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL20457096 0.64 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL24928215 0.64 CYP1A2 (0.35) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD2, OCIAD1 SMN1; SMN2 2384/4885ALDH1A1 1442/4885CA2 2035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.