Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 2/20 | 0.34 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29523864 | 1.00 | P2RX3 (0.39) | P2RX3CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL24894474 | 1.00 | P2RX3 (0.39) | P2RX3CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL26560702 | 1.00 | P2RX3 (0.39) | P2RX3CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL24894483 | 1.00 | P2RX3 (0.39) | P2RX3CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL5161519 | 0.88 | HTRA1 (0.39) | P2RX3CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL29523629 | 0.88 | HTRA1 (0.39) | P2RX3CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL27152355 | 0.86 | HSD17B10 (0.38) | CYP1A2POLBCYP3A4CYP2C19NR1H2 | |
| SCHEMBL29984648 | 0.86 | HSD17B10 (0.38) | CYP1A2POLBCYP3A4CYP2C19NR1H2 | |
| SCHEMBL6857673 | 0.85 | UCHL1 (0.46) | P2RX3CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL10215471 | 0.85 | UCHL1 (0.46) | P2RX3CYP1A2POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |