SCHEMBL26569884

SCHEMBL26569884

Cn1ccc2ccc3ccn(C)c3c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.40
PRKCI P41743 1/20 0.39
BRD4 O60885 1/20 0.37
TAF1 P21675 1/20 0.37
BRPF1 P55201 1/20 0.37
CREBBP Q92793 1/20 0.37
CECR2 Q9BXF3 1/20 0.37
BRD9 Q9H8M2 1/20 0.37
PIK3CB P42338 1/20 0.35
CDK4 P11802 8/20 0.35
CCND1 P24385 8/20 0.35
CCNE2 O96020 6/20 0.35
CCNE1 P24864 6/20 0.35
CDK2 P24941 6/20 0.35
CRBN Q96SW2 1/20 0.33
KDM4E B2RXH2 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
PRKACA P17612 2/20 0.33
PRKACG P22612 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12278805 0.84 CDK4 (0.38) CYP2A6PRKCIPIK3CBCDK4CCND1
SCHEMBL18876190 0.80 CYP2A6 (0.37) CYP2A6PRKCIBRD4TAF1BRPF1
SCHEMBL15450901 0.77 KDM4E (0.33) CYP2A6PRKCICDK4CCND1CCNE2
SCHEMBL24255194 0.77 LMNA (0.42) CYP2A6PRKCIPIK3CBCDK4CCND1
SCHEMBL31057884 0.75 CDK4 (0.35) CYP2A6CDK4CCND1CCNE2CCNE1
SCHEMBL594433 0.75 CDK4 (0.36) CYP2A6CDK4CCND1CCNE2CCNE1
SCHEMBL23059066 0.75 CDK4 (0.34) CYP2A6PRKCICDK4CCND1CCNE2
SCHEMBL13836115 0.75 PSMD14 (0.37) PRKCICDK4CCND1CCNE2CCNE1
SCHEMBL4387353 0.73 PRKCI (0.39) PRKCIPIK3CB
SCHEMBL2052186 0.73 CYP1A2 (0.38) CDK2KDM4EAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OXER1 CYP2A6 1536/4885PRKCI 3910/4885BRD4 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.