Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655356 | 0.87 | ABL1 (0.47) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL2655019 | 0.82 | EGFR (0.43) | ABL1PDGFRBBCRSRCPDGFRA | |
| Hydrochloric Acid SCHEMBL2646707 | 0.80 | ABL1 (0.43) | ABL1PDGFRBBCRSRCPDGFRA | |
| Hydrochloric Acid SCHEMBL9076883 | 0.78 | ABL1 (0.41) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL7829252 | 0.76 | ABL1 (0.46) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL2656336 | 0.75 | ABL1 (0.41) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL2660340 | 0.75 | SYK (0.43) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL7832457 | 0.75 | ABL1 (0.45) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL21362368 | 0.72 | CYP3A4 (0.62) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL8466077 | 0.72 | VCP (0.39) | MAPTALDH1A1KDM4EMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821683-A1 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABA A? RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033192-A1 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABAA RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 1996-10-24 | — | — | WO | disclosed |