Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643607 | 0.89 | HDAC2 (0.39) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL7832457 | 0.84 | ABL1 (0.45) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL2655356 | 0.83 | ABL1 (0.47) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL2649704 | 0.83 | ABL1 (0.45) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL2643125 | 0.81 | SYK (0.37) | MAOAMAOBCYP3A4LMNACYP1A2 | |
| SCHEMBL7832085 | 0.80 | CYP1A2 (0.42) | MAOAMAOBCYP3A4LMNACYP1A2 | |
| SCHEMBL5776863 | 0.77 | MEN1 (0.39) | HDAC1MEN1KMT2AHDAC2 | |
| SCHEMBL2648620 | 0.77 | HDAC3 (0.49) | SRCCYP3A4CYP1A2CYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2646707 | 0.76 | ABL1 (0.43) | ABL1PDGFRBBCRSRCPDGFRA | |
| SCHEMBL2657091 | 0.76 | ABL1 (0.43) | ABL1PDGFRBBCRSRCPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164134-A1 | Benzimidazole compounds and their use as modulators of the GABA A receptor complex | NEUROSEARCH A/S (DK) | 2001-12-19 | — | — | EP | disclosed |
| EP-0821684-B1 | BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS MODULATORS OF THE GABA A? RECEPTOR COMPLEX | NEUROSEARCH AS (DK) | 2001-12-05 | — | — | EP | disclosed |
| US-5922724-A | Benzimidazole compounds and their use as modulators of the GABA a receptor complex | NEUROSEARCH A/S (DK) | 1999-07-13 | — | — | US | disclosed |