Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648450 | 0.82 | BACE1 (0.32) | BACE1 | |
| SCHEMBL6218457 | 0.80 | GABRA1 (0.31) | — | |
| SCHEMBL2659671 | 0.78 | CA1 (0.34) | — | |
| SCHEMBL2649221 | 0.77 | GABRA1 (0.35) | ABL1 | |
| SCHEMBL2659502 | 0.75 | CYP11B1 (0.33) | — | |
| SCHEMBL4491246 | 0.73 | TSHR (0.37) | — | |
| SCHEMBL31048086 | 0.73 | TSHR (0.37) | — | |
| SCHEMBL2649862 | 0.71 | KDM4E (0.38) | — | |
| SCHEMBL2659218 | 0.71 | USP30 (0.36) | BACE1 | |
| SCHEMBL2657259 | 0.71 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074772-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-09-26 | — | — | WO | disclosed |