SCHEMBL26575581

SCHEMBL26575581

Cc1cc(C)c(N2C(CCCc3c(F)c(F)c(F)c(F)c3F)=C(CCCc3c(F)c(F)c(F)c(F)c3F)N(c3c(C)cc(C)cc3C)C2C)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.37
HRH3 Q9Y5N1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27429855 0.82 IDH1 (0.33) IDH1
SCHEMBL10029429 0.81 NPC1 (0.34) HRH3
SCHEMBL26574685 0.75 HRH3 (0.31) IDH1HRH3
SCHEMBL12933708 0.73 HRH3 (0.31) HRH3
SCHEMBL26574626 0.69
SCHEMBL17485782 0.68 ALDH1A1 (0.33) HRH3
SCHEMBL27430107 0.67
SCHEMBL14409969 0.65 KDM4E (0.32)
SCHEMBL27429882 0.65 IDH1 (0.33) IDH1HRH3
SCHEMBL2096180 0.65 IDH1 (0.46) IDH1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023196594-A2 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-12 WO disclosed
WO-2023196602-A1 INFUSION DEVICE FOR THE PREPARATION AND DELIVERY OF MRI PROBES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-12 WO disclosed