Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 9/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | FPR3 | P25089 | 2/20 | 0.31 |
| ▸ | TSPO | P30536 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12933708 | 0.91 | HRH3 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL26575581 | 0.81 | IDH1 (0.37) | HRH3 | |
| SCHEMBL17485782 | 0.73 | ALDH1A1 (0.33) | HTTNPSR1HRH3 | |
| SCHEMBL27429848 | 0.71 | — | — | |
| SCHEMBL26574626 | 0.70 | — | — | |
| SCHEMBL14409969 | 0.70 | KDM4E (0.32) | — | |
| SCHEMBL10029424 | 0.69 | SIRT2 (0.35) | NPC1RAB9ASIRT2CRHR1FPR3 | |
| SCHEMBL30715778 | 0.68 | HTT (0.52) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL25934342 | 0.67 | — | — | |
| SCHEMBL16206237 | 0.66 | POLB (0.34) | HPGDSIRT2CRHR1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713361-B2 | Hydrogenation catalyst compositions and their use for hydrogenation of nitrile rubber | ARLANXEO DEUTSCHLAND GMBH (DE) | 2023-08-01 | — | — | US | disclosed |
| US-11673130-B2 | Catalyst system containing a metathesis catalyst and at least one phenolic compound and a process for metathesis of nitrile-butadiene rubber (NBR) using the catalyst system | ARLANXEO DEUTSCHLAND GMBH (DE) | 2023-06-13 | — | — | US | disclosed |
| WO-2019201730-A1 | HYDROGENATION CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER | ARLANXEO DEUTSCHLAND GMBH (DE) | 2019-10-24 | — | — | WO | disclosed |
| US-20180223005-A1 | CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-10011664-B2 | Functionalized nitrile rubbers and the production thereof | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-07-03 | — | — | US | disclosed |
| US-10000584-B2 | Hydrogenation of nitrile rubber | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| US-9920086-B2 | Ruthenium-based complexes, their preparation and use as catalysts | ARLANXEO DE GMBH (DE) | 2018-03-20 | — | — | US | disclosed |
| US-9828401-B2 | Ruthenium-based complex catalysts | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20170327436-A1 | 1,3-BUTADIENE SYNTHESIS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-9802972-B2 | Ruthenium- or osmium-based complex catalysts | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-10-31 | — | — | US | disclosed |
| US-7662889-B2 | Process for the metathetic degradation of nitrile rubbers | LANXESS DEUTSCHLAND GMBH (DE) | 2010-02-16 | — | — | US | disclosed |
| US-20090076226-A1 | CATALYSTS FOR METATHESIS REACTIONS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090076227-A1 | PROCESS FOR THE METATHETIC DEGRADATION OF NITRILE RUBBER | LANXESS DEUTSCHLAND GMBH (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090069516-A1 | CATALYST SYSTEMS AND THEIR USE FOR METATHESIS REACTIONS | LANXESS DEUTSCHLAND GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090054597-A1 | Metathesis of Nitrile Rubbers In the Presence of Transition Metal Complex Catalysts | LANXESS DEUTSCHLAND GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| US-7470750-B2 | Method for the degradation of nitrile rubber by metathesis in the presence of ruthenium- or osmium-based catalysts | LANXESS DEUTSCHLAND GMBH (DE) | 2008-12-30 | — | — | US | disclosed |
| US-20080076881-A1 | Process for the metathetic degradation of nitrile rubbers | ARLANXEO DEUTSCHLAND GMBH (DE) | 2008-03-27 | — | — | US | disclosed |
| US-20080064822-A1 | Process for degrading nitrile rubbers in the presence of catalysts having an increased activity | ARLANXEO DEUTSCHLAND GMBH (DE) | 2008-03-13 | — | — | US | disclosed |
| US-20070208206-A1 | Novel catalyst systems and a process for reacting chemical compounds in the presence of said catalyst systems | LANXESS DEUTSCHLAND GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| US-20070049700-A1 | Method for the degradation of nitrile rubber by metathesis in the presence of ruthenium- or osmium-based catalysts | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076226-A1 | CATALYSTS FOR METATHESIS REACTIONS | MCM4, MNS1, TERT | NPC1 1101/4885HPGD 1415/4885MAPK1 3196/4885 |
| US-20070208206-A1 | Novel catalyst systems and a process for reacting chemical compounds in the presence of said catalyst systems | NBAS, NNMT, CAT | NPC1 2130/4885HPGD 1458/4885MAPK1 3357/4885 |
| US-20170327436-A1 | 1,3-BUTADIENE SYNTHESIS | SQLE, FDFT1, ENO1 | NPC1 1840/4885HPGD 245/4885MAPK1 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.