Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657740 | 0.91 | GCK (0.64) | GCK | |
| SCHEMBL2656974 | 0.88 | GCK (0.60) | GCK | |
| SCHEMBL16456824 | 0.87 | GCK (0.60) | GCK | |
| SCHEMBL2657827 | 0.87 | GCK (0.49) | GCK | |
| SCHEMBL2655951 | 0.86 | GCK (0.56) | GCKPPARGPPARA | |
| SCHEMBL2656731 | 0.86 | GCK (0.60) | GCK | |
| SCHEMBL2657986 | 0.85 | GCK (0.55) | GCKPPARGPPARA | |
| SCHEMBL2656842 | 0.85 | GCK (0.60) | GCK | |
| SCHEMBL2658943 | 0.84 | GCK (0.66) | GCK | |
| SCHEMBL2656181 | 0.84 | GCK (0.66) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195304-B1 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | ADVINUS THERAPEUTICS PRIVATE LTD (IN) | 2014-01-08 | — | — | EP | claimed |
| EP-2195304-A2 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | Advinus Therapeutics Private Limited (IN) | 2010-06-16 | — | — | EP | claimed |
| WO-2009047798-A2 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2009-04-16 | — | — | WO | claimed |