SCHEMBL2656731

SCHEMBL2656731

O=C(Nc1n[c]cs1)C(Oc1ccc(Cl)cc1)c1ccc(S(=O)(=O)C2CC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2656167 0.91 GCK (0.51) GCK
SCHEMBL2657827 0.90 GCK (0.49) GCK
SCHEMBL2657609 0.86 GCK (0.54) GCK
SCHEMBL2658648 0.85 GCK (0.60) GCK
SCHEMBL2655931 0.84 GCK (0.66) GCK
SCHEMBL2656748 0.83 GCK (0.58) GCK
SCHEMBL2655950 0.82 GCK (0.66) GCK
SCHEMBL2659368 0.80 GCK (0.64) GCK
SCHEMBL2656245 0.80 GCK (0.61) GCK
SCHEMBL2657740 0.80 GCK (0.64) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2195304-B1 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS ADVINUS THERAPEUTICS PRIVATE LTD (IN) 2014-01-08 EP claimed
EP-2195304-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS Advinus Therapeutics Private Limited (IN) 2010-06-16 EP claimed
WO-2009047798-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) 2009-04-16 WO claimed