Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656974 | 0.97 | GCK (0.60) | GCK | |
| SCHEMBL16456824 | 0.96 | GCK (0.60) | GCK | |
| SCHEMBL2657609 | 0.91 | GCK (0.54) | GCK | |
| SCHEMBL2656190 | 0.88 | GCK (0.52) | GCK | |
| SCHEMBL2656167 | 0.87 | GCK (0.51) | GCK | |
| SCHEMBL2656766 | 0.86 | GCK (0.69) | GCK | |
| SCHEMBL2657216 | 0.85 | GCK (0.65) | GCK | |
| SCHEMBL2657143 | 0.85 | GCK (0.70) | GCK | |
| SCHEMBL2658315 | 0.84 | GCK (0.65) | GCK | |
| SCHEMBL2656750 | 0.84 | GCK (0.49) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195304-B1 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | ADVINUS THERAPEUTICS PRIVATE LTD (IN) | 2014-01-08 | — | — | EP | claimed |
| EP-2195304-A2 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | Advinus Therapeutics Private Limited (IN) | 2010-06-16 | — | — | EP | claimed |
| WO-2009047798-A2 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2009-04-16 | — | — | WO | claimed |
| EP-2195304-B1 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | ADVINUS THERAPEUTICS PRIVATE LTD (IN) | 2014-01-08 | — | — | EP | disclosed |