SCHEMBL2656167

SCHEMBL2656167

O=C(Nc1n[c]cs1)C(Oc1ccc(F)cc1)c1ccc(S(=O)(=O)C2CC2)cc1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GCK P35557 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2656731 0.91 GCK (0.60) GCK
SCHEMBL2657827 0.88 GCK (0.49) GCK
SCHEMBL2657740 0.87 GCK (0.64) GCK
SCHEMBL2656974 0.84 GCK (0.60) GCK
SCHEMBL2656604 0.84 GCK (0.66) GCK
SCHEMBL2658026 0.83 GCK (0.52) GCK
SCHEMBL16456824 0.83 GCK (0.60) GCK
SCHEMBL2657609 0.82 GCK (0.54) GCK
SCHEMBL2659320 0.82 GCK (0.62) GCK
SCHEMBL2658893 0.80 GCK (0.60) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2195304-B1 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS ADVINUS THERAPEUTICS PRIVATE LTD (IN) 2014-01-08 — — EP claimed
EP-2195304-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS Advinus Therapeutics Private Limited (IN) 2010-06-16 — — EP claimed
WO-2009047798-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) 2009-04-16 — — WO claimed
EP-2195304-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS Advinus Therapeutics Private Limited (IN) 2010-06-16 — — EP disclosed
WO-2009047798-A2 ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) 2009-04-16 — — WO disclosed
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