Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | PDE2A | O00408 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26577398 | 0.95 | MAPT (0.59) | MAPTPDE2ANPSR1RXFP1PKLR | |
| SCHEMBL26577394 | 0.92 | ALDH1A1 (0.60) | MAPTPDE2ANPSR1RXFP1ALDH1A1 | |
| SCHEMBL26577390 | 0.88 | ALDH1A1 (0.70) | MAPTNPSR1RXFP1ALDH1A1KDM4E | |
| SCHEMBL26780127 | 0.84 | MAPT (0.72) | MAPTPDE2ANPSR1RXFP1PKLR | |
| SCHEMBL26577348 | 0.80 | MAPT (0.66) | MAPTPDE2ANPSR1RXFP1PKLR | |
| SCHEMBL803412 | 0.80 | MAPT (1.00) | MAPTPDE2ANPSR1RXFP1PKLR | |
| SCHEMBL29853434 | 0.80 | MAPT (1.00) | MAPTPDE2ANPSR1RXFP1PKLR | |
| SCHEMBL26780129 | 0.79 | PDE2A (0.65) | MAPTPDE2ANPSR1RXFP1PKLR | |
| SCHEMBL29401099 | 0.76 | PDE2A (1.00) | MAPTPDE2ANPSR1RXFP1PKLR | |
| SCHEMBL29368885 | 0.76 | PDE2A (1.00) | MAPTPDE2ANPSR1RXFP1PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023198486-A1 | UROLITHIN BUTYRATE COMPOUNDS | DSM IP ASSETS B.V. (NL) | 2023-10-19 | — | — | WO | disclosed |