SCHEMBL29401099

SCHEMBL29401099

O=c1oc2cc(O)ccc2c2ccc(O)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 1.00
PKLR P30613 1/20 0.79
NPSR1 Q6W5P4 1/20 0.79
RXFP1 Q9HBX9 1/20 0.79
MAPT P10636 3/20 0.71
KDM4E B2RXH2 4/20 0.65
ALDH1A1 P00352 4/20 0.65
LMNA P02545 2/20 0.65
HSD17B10 Q99714 2/20 0.65
ALOX15 P16050 1/20 0.65
HTT P42858 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
HSD17B3 P37058 3/20 0.65
ESR1 P03372 5/20 0.61
ESR2 Q92731 5/20 0.61
GLA P06280 2/20 0.61
GAA P10253 2/20 0.61
HPGD P15428 2/20 0.61
MAOA P21397 2/20 0.61
KMT2A Q03164 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803408 1.00 PDE2A (1.00) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL29368885 1.00 PDE2A (1.00) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL16663940 0.92 PDE2A (0.85) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL29401241 0.89 NPSR1 (1.00) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL4420540 0.89 NPSR1 (1.00) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL29369247 0.89 NPSR1 (1.00) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL15423100 0.89 PKLR (1.00) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL29369342 0.89 PKLR (1.00) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL15388144 0.88 PDE2A (0.77) PDE2APKLRNPSR1RXFP1MAPT
SCHEMBL1315246 0.88 PDE2A (0.77) PDE2APKLRNPSR1RXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504692-A 3, 8-Dihydroxyl-6H-benzo [ c ] chromen-6-ketone 8-hydroxyl etherified derivatives of phosphodiesterase 2 inhibitor and application thereof 常州大学 2025-02-25 CN claimed
WO-2024252410-A1 SYNERGISTIC BIOACTIVE COMPOSITION FOR ENHANCING ACTIVITY OF PINK1/PARKIN PATHWAY Celagenex Research (India) Pvt. Ltd. (IN) 2024-12-12 WO claimed
WO-2022094174-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ESOPHAGEAL CONDITIONS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2022-05-05 WO claimed
WO-2022040321-A1 PROTECTION AGAINST CORONAVIRUS INFECTION BY EXTRACTS AND EXTRACT COMPONENTS NATREON, INC. (US) 2022-02-24 WO claimed
WO-2025264805-A2 SYNBIOTICS FOR MODULATING GUT MICROFLORA POPULATIONS, TREATMENT OF DYSBIOSIS AND DISEASE PREVENTION, AND METHODS FOR MAKING AND USING SAME PERSEPHONE BIOSCIENCES, INC. (US) 2025-12-26 WO disclosed
EP-4578500-A2 COMPOSITIONS AND METHODS FOR IMPROVING MITOCHONDRIAL FUNCTION AND TREATING NEURODEGENERATIVE DISEASES AND COGNITIVE DISORDERS Amazentis SA (CH) 2025-07-02 EP disclosed
US-20250090479-A1 COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS IIera Derm LLC 2025-03-20 US disclosed
EP-3369420-B1 NON-THERAPEUTIC USE OF UROLITHIN A FOR IMPROVING COGNITIVE FUNCTION. AMAZENTIS SA (CH) 2025-03-12 EP disclosed
EP-3372228-B1 NON-THERAPEUTIC METHOD OF INCREASING OR MAINTAINING MITOCHONDRIAL FUNCTION AMAZENTIS SA (CH) 2025-03-12 EP disclosed
CN-119504692-A 3, 8-Dihydroxyl-6H-benzo [ c ] chromen-6-ketone 8-hydroxyl etherified derivatives of phosphodiesterase 2 inhibitor and application thereof 常州大学 2025-02-25 CN disclosed
US-20250032565-A1 METHOD AND COMPOSITION FOR PRODUCTION OF A PHYTONUTRIENT IN A MICROBIOME ACCESS BUSINESS GROUP INTERNATIONAL LLC 2025-01-30 US disclosed
WO-2024252410-A1 SYNERGISTIC BIOACTIVE COMPOSITION FOR ENHANCING ACTIVITY OF PINK1/PARKIN PATHWAY Celagenex Research (India) Pvt. Ltd. (IN) 2024-12-12 WO disclosed
CN-116774524-A Photosensitive resin composition, method for producing pattern cured product, and use thereof 武汉柔显科技股份有限公司 2023-09-19 CN disclosed
EP-4153306-A1 COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS Ilera Derm LLC (US) 2023-03-29 EP disclosed
WO-2022229417-A1 NOVEL HETEROCYCLIC COMPOUNDS Floratek Pharma SA (CH) 2022-11-03 WO disclosed
US-20220233627-A1 COMPOSITIONS COMPRISING PLANT EXTRACTS AND OILS AND RELATED METHODS OF TREATMENT AND THEIR PREPARATION LE NADUR, LLC 2022-07-28 US disclosed
CN-114732814-A Application of urolithin A in preventing and treating allergic rhinitis and allergic asthma 中山大学 2022-07-12 CN disclosed
WO-2022094174-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ESOPHAGEAL CONDITIONS CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2022-05-05 WO disclosed
CN-114423420-A Methods and compositions for producing phytonutrients in microbiome 捷通国际有限公司 2022-04-29 CN disclosed
WO-2022040321-A1 PROTECTION AGAINST CORONAVIRUS INFECTION BY EXTRACTS AND EXTRACT COMPONENTS NATREON, INC. (US) 2022-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250090479-A1 COMPOSITIONS FOR TREATING ACNE AND DERMATOLOGICAL CONDITIONS COQ8A, ATP5ME, AGK PDE2A 1915/4885PKLR 2812/4885NPSR1 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.