Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197402 | 0.84 | TSHR (0.53) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL31292947 | 0.79 | MGAM (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3676085 | 0.78 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL3676083 | 0.78 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL13296224 | 0.78 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL25600165 | 0.78 | TSHR (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL7888718 | 0.77 | TSHR (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL16256492 | 0.77 | TSHR (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL13039797 | 0.77 | ALDH1A1 (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL5000149 | 0.77 | TSHR (0.46) | TSHRHSD17B10MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040194-A1 | CONDITIONING FOR IN VIVO IMMUNE CELL ENGINEERING | CAPSTAN THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2024040195-A1 | CONDITIONING FOR IN VIVO IMMUNE CELL ENGINEERING | CAPSTAN THERAPEUTICS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |
| WO-2023196445-A1 | PEG-LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |