SCHEMBL5000149

SCHEMBL5000149

COC(=O)CC(CO)CO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
HSD17B10 Q99714 2/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
KMT2A Q03164 2/20 0.34
TET2 Q6N021 1/20 0.34
MEN1 O00255 1/20 0.34
TGFBR1 P36897 1/20 0.34
MAPT P10636 3/20 0.33
LMNA P02545 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23443024 0.88 TSHR (0.40) TSHRHSD17B10MGAMGAASI
SCHEMBL11868062 0.86 TSHR (0.39) TSHRHSD17B10MGAMGAASI
SCHEMBL3197402 0.86 TSHR (0.53) TSHRHSD17B10MGAMGAASI
SCHEMBL28228511 0.84 TSHR (0.37) TSHRHSD17B10MGAMGAASI
SCHEMBL15242341 0.80 TSHR (0.50) TSHRKMT2AMEN1MAPTLMNA
SCHEMBL16256492 0.79 TSHR (0.46) TSHRHSD17B10MGAMGAASI
SCHEMBL7888718 0.79 TSHR (0.46) TSHRHSD17B10MGAMGAASI
SCHEMBL12940852 0.78 TSHR (0.40) TSHRHSD17B10MGAMGAASI
SCHEMBL12295406 0.78 TSHR (0.40) TSHRHSD17B10MGAMGAASI
SCHEMBL1541120 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638969-A Degradable aromatic polyester polymer and synthesis method thereof 青岛大学 2025-03-18 CN claimed
CN-114940864-B Kindergarten wall based on novel erasable coating 南通市建筑设计研究院有限公司 2023-08-29 CN claimed
CN-114940864-A Infant garden wall surface based on novel erasable coating 南通市建筑设计研究院有限公司 2022-08-26 CN claimed
CN-100400567-C Method for producing polyetherols BASF AG (DE) 2008-07-09 CN claimed
US-7241914-B2 Method for producing polyesterpolyols of polyvalent alcohols BASF AKTIENGESELLSCHAFT (DE) 2007-07-10 US claimed
CN-1656147-A Method for producing polyetherols BASF AG (DE) 2005-08-17 CN claimed
US-20050148802-A1 Method for producing polyetherols BASF AKTIENGESELLSCHAFT 2005-07-07 US claimed
CN-1585736-A Method for producing (meth)acrylic acid esters of polyhydric alcohols BASF AG (DE) 2005-02-23 CN claimed
US-20050010065-A1 Method for producing (meth) acrylic acid esters of polyhydric alcohols BASF AKTIENGESELLSCHAFT (DE) 2005-01-13 US claimed
CN-1518567-A Linear block polymer ������������� 2004-08-04 CN claimed
EP-0866816-B1 LINEAR BLOCK POLYMER COMPRISING UREA AND URETHANE GROUPS, METHOD FOR THE PRODUCTION OF LINEAR BLOCK POLYMERS AND USE OF THE BLOCK POLYMERS AS IMPLANTS ARTIMPLANT DEV ARTDEV AB (SE) 2001-05-30 EP claimed
US-6210441-B1 BIOLOGICALLY DEGRADABLE AND CAN BE EXCRETED FROM A HUMAN BODY ARTIMPLANT DEVELOPMENT ARTDEV AB (SE) 2001-04-03 US claimed
CN-1214057-A Linear block polymer comprising urea and urethane groups, method for prepn. of linear block polymers and use of block polymers as implants ATEM POLYRAND AB (SE) 1999-04-14 CN claimed
EP-0866816-A1 LINEAR BLOCK POLYMER COMPRISING UREA AND URETHANE GROUPS, METHOD FOR THE PRODUCTION OF LINEAR BLOCK POLYMERS AND USE OF THE BLOCK POLYMERS AS IMPLANTS Artimplant Development Artdev AB (SE) 1998-09-30 EP claimed
WO-1997022643-A1 LINEAR BLOCK POLYMER COMPRISING UREA AND URETHANE GROUPS, METHOD FOR THE PRODUCTION OF LINEAR BLOCK POLYMERS AND USE OF THE BLOCK POLYMERS AS IMPLANTS ARTIMPLANT DEVELOPMENT ARTDEV AB (SE) 1997-06-26 WO claimed
JP-58189261-A None JP disclosed
JP-61126143-A None JP disclosed
JP-S61126143-A PRODUCTION OF ANTICOAGULANT MATERIAL IMANISHI YUKIO 1986-06-13 JP disclosed
JP-S58189261-A POLYESTER RESIN COMPOSITION FOR HOT-MELT COATING SHOWA ELECTRIC WIRE & CABLE CO LTD 1983-11-04 JP disclosed
US-4373059-A Pre-condensed, thermosetting aqueous varnish coating agent and its utilization for cathodic deposition upon electrically conducting surfaces HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050010065-A1 Method for producing (meth) acrylic acid esters of polyhydric alcohols ADH1A, ADH1C, ADH5 TSHR 2220/4885HSD17B10 845/4885MGAM 242/4885
US-20050148802-A1 Method for producing polyetherols ADH1A, ADH1C, ADH5 TSHR 3289/4885HSD17B10 85/4885MGAM 924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.