SCHEMBL26580966

SCHEMBL26580966

NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.64
KMT2A Q03164 4/20 0.58
GAA P10253 1/20 0.58
TSHR P16473 2/20 0.56
MEN1 O00255 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
HPGD P15428 2/20 0.56
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
MCL1 Q07820 1/20 0.53
MMP2 P08253 1/20 0.53
RECQL P46063 1/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53
HTT P42858 1/20 0.51
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26581057 1.00 AOC3 (0.64) AOC3KMT2AGAATSHRMEN1
SCHEMBL417953 0.93 AOC3 (0.72) AOC3KMT2AGAATSHRMEN1
Bromide SCHEMBL10352605 0.91 AOC3 (0.70) AOC3KMT2AGAATSHRMEN1
Hydrochloric Acid SCHEMBL12478237 0.91 AOC3 (0.73) AOC3KMT2AGAATSHRMEN1
SCHEMBL25410244 0.85 GAA (0.61) KMT2AGAATSHRMEN1CYP1A2
SCHEMBL25412009 0.83 GAA (0.63) KMT2AGAATSHRMEN1CYP1A2
Trifluoroacetic Acid SCHEMBL7760563 0.83 AOC3 (0.60) AOC3KMT2AGAATSHRMEN1
SCHEMBL25874786 0.83 CA2 (0.56) GAAHPGDCA1CA2MMP2
SCHEMBL13073870 0.82 AOC3 (0.73) AOC3KMT2AGAAMEN1CA1
SCHEMBL14697332 0.81 GAA (0.61) KMT2AGAATSHRMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330254-A1 ANTI-GLP1R ANTIBODY-TETHERED DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330254-A1 ANTI-GLP1R ANTIBODY-TETHERED DRUG CONJUGATES COMPRISING GLP1 PEPTIDOMIMETICS AND USES THEREOF GLP1R, GIPR, GCGR AOC3 3915/4885KMT2A 1978/4885GAA 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.