Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10352605 | 0.98 | AOC3 (0.70) | AOC3GAAKMT2ATSHRMEN1 | |
| Hydrochloric Acid SCHEMBL12478237 | 0.98 | AOC3 (0.73) | AOC3GAAKMT2ATSHRMEN1 | |
| SCHEMBL26580966 | 0.93 | AOC3 (0.64) | AOC3GAAKMT2ATSHRMEN1 | |
| SCHEMBL26581057 | 0.93 | AOC3 (0.64) | AOC3GAAKMT2ATSHRMEN1 | |
| Trifluoroacetic Acid SCHEMBL7760563 | 0.89 | AOC3 (0.60) | AOC3GAAKMT2ATSHRMEN1 | |
| SCHEMBL13073870 | 0.89 | AOC3 (0.73) | AOC3GAAKMT2AMEN1CA1 | |
| SCHEMBL15680124 | 0.86 | AOC3 (0.75) | AOC3GAATSHRCYP1A2CYP2D6 | |
| SCHEMBL7353744 | 0.86 | GAA (0.75) | GAAKMT2ATSHRMEN1CYP1A2 | |
| SCHEMBL8935238 | 0.85 | LTA4H (0.67) | KMT2ATSHRHPGDRECQLALDH1A1 | |
| SCHEMBL27634241 | 0.85 | TP53 (0.62) | AOC3GAAKMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192629-A1 | INDUCTION OF MECP2 EXPRESSION BY DNA METHYL TRANSFERASE INHIBITORS | HEROPHILUS, INC. (US) | 2023-10-05 | — | — | WO | claimed |
| EP-2385948-B1 | FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | TORRENT PHARMACEUTICALS LTD (IN) | 2017-10-04 | — | — | EP | claimed |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| EP-2892343-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-07-15 | — | — | EP | claimed |
| WO-2014037349-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2014-03-13 | — | — | WO | claimed |
| US-20130331406-A1 | NOVEL FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2013-12-12 | — | — | US | claimed |
| US-8541430-B2 | Fused thiazolo and oxazolo pyrimidinones | TORRENT PHARMACEUTICALS LIMITED (IN) | 2013-09-24 | — | — | US | claimed |
| US-20100087440-A1 | Phosphatidylinositol 3-Kinase Inhibitors and Methods of Their Use | EXELIXIS, INC. | 2010-04-08 | — | — | US | claimed |
| EP-2139483-A2 | COMBINATION THERAPIES COMPRISING QUINOXALINE INHIBITORS OF PI3K-ALPHA FOR USE IN THE TREATMENT OF CANCER | Exelixis, Inc. (US) | 2010-01-06 | — | — | EP | claimed |
| CN-101497613-A | Preparation of praziquanamine | FUYANG GENEBEST CHEMICAL INDUS (CN) | 2009-08-05 | — | — | CN | claimed |
| WO-2008127594-A2 | COMBINATION THERAPIES COMPRISING QUINOXALINE INHIBITORS OF PI3K-ALPHA FOR USE IN THE TREATMENT OF CANCER | EXELIXIS, INC. (US) | 2008-10-23 | — | — | WO | claimed |
| WO-2008100727-A2 | HIGH-DOSE GLYCINE AS A TREATMENT FOR OBSESSIVE-COMPULSIVE DISORDER AND OBSESSIVE-COMPULSIVE SPECTRUM DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-08-21 | — | — | WO | claimed |
| US-20080166359-A1 | Methods of using MEK inhibitors | EXELIXIS, INC. | 2008-07-10 | — | — | US | claimed |
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |
| EP-0230151-A2 | Cholecystokinin antagonists | BIOMEASURE, INC. (US) | 1987-07-29 | — | — | EP | claimed |
| US-12391693-B2 | Solid polymorphs of a FLNA-binding compound and its hydrochloride salts | CASSAVA SCIENCES, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| CN-114072406-B | Solid polymorphs of FLNA-binding compounds and hydrochloride salts thereof | 卡萨瓦科学公司 | 2025-03-18 | — | — | CN | disclosed |
| US-4094986-A | BACTERICIDES, FUNGICIDES | M. S. & D. (I.A.) CORP. (US) | 1978-06-13 | — | — | US | disclosed |
| US-4079051-A | 4-Halogeno-s-triazin-2-yl-phosphoramide acid containing reactive dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4033944-A | Fibre-reactive hydroxycycloalkenyl-halo triazinyl containing dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087440-A1 | Phosphatidylinositol 3-Kinase Inhibitors and Methods of Their Use | PIK3CA, PIK3CB, PIK3CG | AOC3 4082/4885GAA 1284/4885KMT2A 2013/4885 |
| US-20130331406-A1 | NOVEL FUSED THIAZOLO AND OXAZOLO PYRIMIDINONES | TPMT, TYMS, UGT1A8 | AOC3 2477/4885GAA 2361/4885KMT2A 4204/4885 |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | CAT, HSF1, HPD | AOC3 427/4885GAA 170/4885KMT2A 3258/4885 |
| US-20080166359-A1 | Methods of using MEK inhibitors | BRAF, NRAS, KRAS | AOC3 3166/4885GAA 2414/4885KMT2A 669/4885 |
| US-12391693-B2 | Solid polymorphs of a FLNA-binding compound and its hydrochloride salts | FLNA, FLNB, TOP2A | AOC3 4526/4885GAA 4136/4885KMT2A 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.