SCHEMBL26582014

SCHEMBL26582014

N#Cc1cc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)ccc1-c1ccccc1-c1ccccc1-c1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1C#N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
KDM4E B2RXH2 1/20 0.46
HTT P42858 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
XDH P47989 3/20 0.44
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
ABCG2 Q9UNQ0 4/20 0.41
ABCB1 P08183 2/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26582015 0.97 XDH (0.45) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL26582017 0.94 XDH (0.43) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25774993 0.93 XDH (0.43) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL26553184 0.93 ALDH1A1 (0.41) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25774929 0.93 ALDH1A1 (0.41) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL26553187 0.92 ALDH1A1 (0.43) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25774930 0.92 ALDH1A1 (0.43) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL25774192 0.92 ALDH1A1 (0.43) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL31663619 0.92 XDH (0.51) ALDH1A1KDM4EHTTRXFP1LMNA
SCHEMBL26582016 0.90 ALDH1A1 (0.44) ALDH1A1KDM4EHTTRXFP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023195735-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-10-12 WO disclosed