Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658565 | 1.00 | POLB (0.56) | POLBDRD2DRD4DRD3LMNA | |
| SCHEMBL2658444 | 0.88 | POLB (0.52) | POLBDRD2DRD4DRD3LMNA | |
| SCHEMBL16824855 | 0.83 | POLB (0.73) | POLBLMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2662545 | 0.83 | KDM4E (0.50) | POLBDRD2DRD4DRD3LMNA | |
| SCHEMBL2662051 | 0.83 | MGLL (0.58) | POLBLMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2627249 | 0.82 | MAPT (0.69) | LMNAMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL8440523 | 0.82 | MAPT (0.56) | POLBDRD2DRD4DRD3LMNA | |
| SCHEMBL2661913 | 0.82 | POLB (0.50) | POLBDRD2DRD4DRD3LMNA | |
| SCHEMBL520396 | 0.82 | HTR7 (0.56) | DRD2DRD4DRD3LMNAMAPT | |
| SCHEMBL2661929 | 0.82 | SMN1; SMN2 (0.57) | POLBDRD2DRD3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-A1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH A/S (DK) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078728-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH A/S (DK) | 2000-12-28 | — | — | WO | disclosed |