Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | GCK | P35557 | 13/20 | 0.56 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423116 | 0.88 | KCNH2 (0.63) | KCNH2GCKFFAR2SCN5A | |
| SCHEMBL2642308 | 0.88 | KCNH2 (0.63) | KCNH2GCKFFAR2SCN5A | |
| SCHEMBL2642073 | 0.85 | GCK (0.76) | KCNH2GCKFFAR2 | |
| SCHEMBL2642135 | 0.82 | GCK (0.75) | KCNH2GCKFFAR2 | |
| SCHEMBL2642057 | 0.81 | FFAR2 (0.56) | KCNH2GCKFFAR2SCN5A | |
| SCHEMBL14423112 | 0.81 | FFAR2 (0.56) | KCNH2GCKFFAR2SCN5A | |
| SCHEMBL14423113 | 0.81 | FFAR2 (0.56) | KCNH2GCKFFAR2SCN5A | |
| SCHEMBL2642131 | 0.81 | FFAR2 (0.56) | KCNH2GCKFFAR2SCN5A | |
| SCHEMBL2657428 | 0.79 | KCNH2 (0.84) | KCNH2GCKFFAR2 | |
| SCHEMBL2646398 | 0.79 | KCNH2 (0.84) | KCNH2GCKFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003095438-A9 | SUBSTITUTED PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-12-23 | — | — | WO | claimed |