Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265318 | 0.81 | CYP19A1 (0.38) | CYP19A1 | |
| SCHEMBL10374 | 0.80 | CYP19A1 (0.34) | CYP19A1 | |
| SCHEMBL6250570 | 0.75 | — | — | |
| SCHEMBL3303673 | 0.70 | — | — | |
| SCHEMBL2656741 | 0.68 | ALDH1A1 (0.38) | CYP19A1 | |
| SCHEMBL2650266 | 0.68 | ALDH1A1 (0.40) | — | |
| SCHEMBL2659464 | 0.67 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL9834056 | 0.66 | CYP19A1 (0.41) | CYP19A1 | |
| SCHEMBL10529106 | 0.66 | MEN1 (0.32) | — | |
| SCHEMBL7259821 | 0.66 | FOLH1 (0.35) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333336-B1 | GAMMA-AMINOBUTYRIC ACID RECEPTORS AS ANTICONVULSANTS FORMING THE COMPOUND BY AMIDATION | MERCK SHARP & DOHME LTD. (GB) | 2001-12-25 | — | — | US | disclosed |
| EP-1064283-A1 | PYRAZOLO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999048892-A1 | PYRAZOLO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1999-09-30 | — | — | WO | disclosed |