Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 10/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.38 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GCG | P01275 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.36 |
| ▸ | ADCY6 | O43306 | 3/20 | 0.36 |
| ▸ | ADCY3 | O60266 | 3/20 | 0.36 |
| ▸ | ADCY9 | O60503 | 3/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.36 |
| ▸ | ADCY7 | P51828 | 3/20 | 0.36 |
| ▸ | ADCY2 | Q08462 | 3/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.36 |
| ▸ | ADCY4 | Q8NFM4 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654298 | 0.94 | LMNA (0.44) | LMNAGCGRL3MBTL1KCNK2KCNK10 | |
| SCHEMBL2659923 | 0.89 | GCGR (0.45) | GCGRKCNK2GCGADCY6ADCY3 | |
| SCHEMBL2660139 | 0.88 | GCGR (0.40) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2654573 | 0.88 | GCGR (0.49) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2654228 | 0.88 | GCGR (0.40) | GCGRGCGADCY6ADCY3ADCY9 | |
| SCHEMBL2653443 | 0.87 | GCGR (0.44) | GCGRKCNK2KCNK10ADCY6ADCY3 | |
| SCHEMBL2659948 | 0.86 | GCGR (0.49) | GCGRADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL2660316 | 0.86 | GCGR (0.45) | GCGRGCGADCY6ADCY3ADCY9 | |
| SCHEMBL2665073 | 0.84 | GCGR (0.43) | GCGRGCGGLP1R | |
| SCHEMBL2660535 | 0.84 | GCGR (0.43) | GCGRGCGGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152750-A1 | Novel glucagon antagonists | NOVO NORDISK A/S (DK) | 2004-08-05 | — | — | US | disclosed |
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004056763-A2 | NOVEL GLUCAGON ANTAGONISTS | NOVO NORDISK A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152750-A1 | Novel glucagon antagonists | GLP1R, GCGR, GIPR | LMNA 4032/4885GCGR 2/4885L3MBTL1 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.