Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.31 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2660948 | 0.93 | SLC2A1 (0.32) | SLC2A1HDAC1FAAHTUBB4ATUBB | |
| Trifluoroacetic Acid SCHEMBL2659980 | 0.88 | — | — | |
| Trifluoroacetic Acid SCHEMBL2660407 | 0.87 | MEN1 (0.40) | OGA | |
| Trifluoroacetic Acid SCHEMBL2660194 | 0.86 | PIK3CD (0.34) | OGA | |
| Trifluoroacetic Acid SCHEMBL27763020 | 0.86 | SLC2A1 (0.32) | SLC2A1HDAC1TUBB4ATUBBTUBA3C | |
| Trifluoroacetic Acid SCHEMBL27762858 | 0.83 | OGA (0.31) | SLC2A1OGA | |
| Trifluoroacetic Acid SCHEMBL2659546 | 0.83 | NPC1 (0.35) | SLC2A1HDAC1FAAHOGA | |
| Trifluoroacetic Acid SCHEMBL2660400 | 0.83 | AGTR2 (0.32) | SLC2A1OGAAGTR2 | |
| Trifluoroacetic Acid SCHEMBL27763028 | 0.82 | PDCD1 (0.34) | OGA | |
| Trifluoroacetic Acid SCHEMBL2660120 | 0.82 | CCNT1 (0.30) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |