Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2659234 | 0.94 | MEN1 (0.37) | MEN1KMT2AALDH1A1MAPK1GAA | |
| Trifluoroacetic Acid SCHEMBL2661412 | 0.92 | MEN1 (0.36) | MEN1KMT2AALDH1A1MAPK1GAA | |
| Trifluoroacetic Acid SCHEMBL2659467 | 0.89 | MEN1 (0.34) | MEN1KMT2AALDH1A1MAPK1GAA | |
| Trifluoroacetic Acid SCHEMBL2660194 | 0.88 | PIK3CD (0.34) | OGA | |
| Trifluoroacetic Acid SCHEMBL2659557 | 0.87 | SLC2A1 (0.33) | OGA | |
| Trifluoroacetic Acid SCHEMBL27763028 | 0.84 | PDCD1 (0.34) | OGA | |
| Trifluoroacetic Acid SCHEMBL2659328 | 0.84 | OGA (0.32) | OGA | |
| SCHEMBL2659559 | 0.83 | PIK3CD (0.36) | MEN1KMT2AOGA | |
| Trifluoroacetic Acid SCHEMBL2659546 | 0.82 | NPC1 (0.35) | ALDH1A1OGAPOLBATM | |
| Trifluoroacetic Acid SCHEMBL2660327 | 0.82 | S1PR1 (0.32) | MEN1KMT2AALDH1A1GAAOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |