Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.36 |
| ▸ | OGA | O60502 | 4/20 | 0.36 |
| ▸ | SCN1A | P35498 | 3/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2660194 | 0.96 | PIK3CD (0.34) | PIK3CDPIK3CAPIK3CBPIK3CGOGA | |
| Trifluoroacetic Acid SCHEMBL2660893 | 0.88 | DDR1 (0.35) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| Trifluoroacetic Acid SCHEMBL2660407 | 0.83 | MEN1 (0.40) | OGAMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL2659557 | 0.81 | SLC2A1 (0.33) | OGA | |
| SCHEMBL2668777 | 0.81 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGOGA | |
| Trifluoroacetic Acid SCHEMBL27763028 | 0.80 | PDCD1 (0.34) | PIK3CDPIK3CGOGACD274 | |
| SCHEMBL9073010 | 0.80 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBPIK3CGOGA | |
| SCHEMBL2659561 | 0.80 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBPIK3CGOGA | |
| SCHEMBL2972367 | 0.80 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBPIK3CGOGA | |
| SCHEMBL13203629 | 0.78 | PIK3CD (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |