Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713081 | 0.81 | DGAT1 (0.45) | HDAC1HDAC6KDM4EKMT2AL3MBTL1 | |
| SCHEMBL21450809 | 0.81 | HDAC1 (0.44) | HDAC1HDAC6KDM4EKMT2AKCNQ3 | |
| SCHEMBL123712 | 0.77 | HDAC1 (0.52) | HDAC1HDAC6KDM4EKMT2AKCNQ3 | |
| SCHEMBL18460741 | 0.77 | MAPK1 (0.34) | HDAC1HDAC6KDM4EMAPK1L3MBTL1 | |
| SCHEMBL8192122 | 0.77 | HDAC1 (0.52) | HDAC1HDAC6KDM4EKMT2AKCNQ3 | |
| SCHEMBL21004360 | 0.76 | HDAC1 (0.61) | HDAC1HDAC6KDM4EKMT2AKCNQ3 | |
| SCHEMBL12204514 | 0.76 | HDAC1 (0.52) | HDAC1HDAC6KDM4EMAPK1KMT2A | |
| SCHEMBL13864292 | 0.76 | HDAC1 (0.52) | HDAC1HDAC6KDM4EKMT2AKCNQ3 | |
| SCHEMBL30574349 | 0.76 | MAPK1 (0.67) | HDAC1HDAC6KDM4EMAPK1KMT2A | |
| SCHEMBL64763 | 0.76 | MAPK1 (0.67) | HDAC1HDAC6KDM4EMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406620-B1 | VINYL PHENYL DERIVATIVES AS GLK ACTIVATORS | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | EP | disclosed |