Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6422585 | 0.87 | CFD (0.56) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL4815909 | 0.86 | KDM4E (0.74) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL31370745 | 0.86 | KDM4E (0.74) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL4816031 | 0.85 | KDM4E (0.64) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL6422580 | 0.84 | PDGFRB (0.54) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL14700502 | 0.83 | KDM4E (0.70) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL14700438 | 0.83 | KDM4E (0.70) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL17775015 | 0.83 | KDM4E (0.70) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL11150792 | 0.83 | KDM4E (0.70) | XDHKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL17775014 | 0.83 | KDM4E (0.70) | XDHKDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |