Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E3 | Q9Y5X4 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.52 |
| ▸ | COMT | P21964 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748600 | 1.00 | NR2E3 (0.62) | NR2E3KMT2ATP53MAPTKDM4E | |
| SCHEMBL31748608 | 0.91 | NR2E3 (0.63) | NR2E3KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL26597196 | 0.91 | NR2E3 (0.63) | NR2E3KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL26597195 | 0.85 | ALDH1A1 (0.68) | NR2E3KMT2ATP53MAPTKDM4E | |
| SCHEMBL31748596 | 0.85 | NR2E3 (0.62) | NR2E3KMT2ATP53MAPTKDM4E | |
| SCHEMBL26597189 | 0.85 | NR2E3 (0.62) | NR2E3KMT2ATP53MAPTKDM4E | |
| SCHEMBL31748716 | 0.85 | ALDH1A1 (0.68) | NR2E3KMT2ATP53MAPTKDM4E | |
| SCHEMBL30667673 | 0.85 | ALDH1A1 (0.68) | NR2E3KMT2ATP53MAPTKDM4E | |
| SCHEMBL31748782 | 0.84 | NR2E3 (0.57) | NR2E3KMT2ATP53MAPTKDM4E | |
| SCHEMBL26597190 | 0.84 | NR2E3 (0.57) | NR2E3KMT2ATP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023203161-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | UNIVERSITE PARIS CITE (FR) | 2023-10-26 | — | — | WO | disclosed |
| EP-4265246-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2023-10-25 | — | — | EP | disclosed |
| EP-4265246-A1 | COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS | Université Paris Cité (FR) | 2023-10-25 | — | — | EP | disclosed |